The results have been submitted to the Lancet.
While co-administering Covid boosters and flu shots will be demanding for GPs, Dr Lazarus said it is common to receive more than one vaccine at a time, particularly in childhood and for foreign travel. When asked at the end of the study, 97% of the volunteers said they would be willing to have two vaccines at the same appointment in the future. Among the rare reports of severe reactions was one person who was admitted to hospital with a migraine. Two to three weeks after that, the volunteers returned again to discuss any side-effects and provide a blood sample.Ībout three-quarters of the volunteers reported at least one systemic side-effect, such as fatigue, regardless of whether they had the Covid shot alone or in combination with a flu shot. Three to four weeks later, the participants returned and had either a placebo shot or a flu vaccine, depending on which they missed at the first appointment. The older group received the FluAd jab made by Seqirus in the UK, while the younger group had either Flublok from Sanofi or Flucelvax, also from Seqirus. At their first appointment, they received either a Covid shot and a flu shot, or a Covid shot and a placebo. The volunteers were divided into two age groups, the under-65s and the 65s and over. The trial, which took place across 12 NHS sites in England and Wales, looked at the side-effects and immune responses when 679 people had their second shot of Pfizer or AstraZeneca Covid vaccine in one arm followed by one of three flu vaccines in the other. The JCVI’s advice comes amid concerns that the coming flu season could be worse than in recent years because people’s immunity to influenza will have waned. “We don’t expect, with booster doses, that there would be an impact on how well the Covid vaccine works,” she said.
Side effects of flu shot trial#
Researchers on the Combining Influenza and Covid-19 Vaccination (ComFluCov) study said the findings supported recent advice from the Joint Committee on Vaccination and Immunisation (JCVI) to offer Covid boosters alongside flu jabs this autumn and winter, where it is practical to do so.ĭr Rajeka Lazarus, the lead scientist on the trial and a consultant in infectious diseases and microbiology at University Hospitals Bristol and Weston NHS Foundation Trust, said the results, which are preliminary and not yet peer-reviewed, were “a really positive step” that could mean fewer appointments for those eligible for boosters and flu shots. The most common side effects included pain at the injection site and temporary fatigue, headache or muscle pain.īlood tests on the trial volunteers suggest there was no negative impact on the immune responses to either flu or Covid vaccines when the shots were given one after the other, in opposite arms, though one of the flu vaccines, FluBlok by Sanofi, appeared to be more potent when given alongside the Pfizer jab. While some people experienced more side-effects with certain combinations of flu and Covid shots, the ailments were mainly mild to moderate, the study found. The Associated Press contributed to this report.Flu jabs are safe to give at the same time as the Pfizer or AstraZeneca Covid vaccines, according to the first clinical trial to investigate co-administering the shots in a single appointment.
If you’re experiencing a severe allergic reaction, the signs would most likely happen within a few minutes to a few hours after the vaccine is given.ĭespite possible side effects, the CDC says the flu vaccine is “the first and best way to reduce your chances of getting the flu and spreading it to others.” Life-threatening allergic reactions to the flu shot are rare, the CDC said. Here are the signs of a severe allergic reaction, according to the CDC: The CDC said that with any vaccine, you should watch for any unusual conditions, such as high fever, behavior changes, or signs of a severe allergic reaction after getting vaccinated. The CDC also said that some studies have found a possible small association of injectable flu vaccine with Guillain-Barré syndrome.The flu shot, like other injections, can occasionally cause fainting.Soreness, redness, and/or swelling from the shot.Here are the common side effects from the flu shot, according to the CDC: The CDC said the good news is that the side effects are generally mild and go away within a few days. If you’re planning on getting a flu vaccine, there’s a chance you could experience side effects. Prepare now: At-home tests and other things you need in your home sick kit
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